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Shoji Kubo Selected Research

Methylene Chloride (Dichloromethane)

4/2020Multiple cholangiocarcinomas in the intrahepatic and extrahepatic biliary tree due to dichloromethane exposure: a case report.
4/2019Occupational cholangiocarcinoma diagnosed 18 years after the end of exposure to 1,2-dichloropropane and dichloromethane at a printing company: a case report.
3/2018Occupational cholangiocarcinoma caused by exposure to 1,2-dichloropropane and/or dichloromethane.
9/2016Outcomes after resection of occupational cholangiocarcinoma.
1/2015Severe acute hepatitis in a printing company worker: a case study.
1/2014Different carcinogenic process in cholangiocarcinoma cases epidemically developing among workers of a printing company in Japan.

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Shoji Kubo Research Topics

Disease

89Neoplasms (Cancer)
08/2022 - 06/2002
87Hepatocellular Carcinoma (Hepatoma)
01/2022 - 04/2002
32Cholangiocarcinoma
11/2022 - 05/2004
30Fibrosis (Cirrhosis)
05/2022 - 04/2002
21Infections
08/2021 - 04/2002
19Neoplasm Metastasis (Metastasis)
03/2022 - 03/2002
18Hepatitis
01/2015 - 12/2002
11Liver Cirrhosis (Hepatic Cirrhosis)
07/2022 - 05/2004
11Lymphatic Metastasis
03/2022 - 03/2002
8Hemorrhage
01/2021 - 03/2003
8Chronic Hepatitis C
10/2020 - 11/2005
7Liver Diseases (Liver Disease)
01/2021 - 08/2004
7Carcinoma (Carcinomatosis)
03/2019 - 07/2002
5Carcinogenesis
03/2021 - 08/2005
5Liver Failure
12/2017 - 02/2004
5Margins of Excision
04/2014 - 03/2002
5Thrombosis (Thrombus)
09/2009 - 01/2002
4Pancreatic Neoplasms (Pancreatic Cancer)
05/2022 - 03/2003
4Surgical Wound Infection
07/2021 - 03/2013
4Biliary Tract Neoplasms (Biliary Tract Cancer)
03/2021 - 10/2014
4Adenocarcinoma
05/2020 - 05/2004
4Liver Neoplasms (Liver Cancer)
10/2019 - 04/2015
4Cholangitis
03/2019 - 06/2002
4Inflammation (Inflammations)
04/2015 - 11/2004
3Colorectal Neoplasms (Colorectal Cancer)
03/2022 - 11/2018
3Wounds and Injuries (Trauma)
09/2021 - 01/2002
3Diabetes Mellitus
09/2021 - 07/2004
3Pancreaticobiliary Maljunction
03/2021 - 03/2019
3Necrosis
01/2021 - 12/2006
3Rupture
04/2019 - 03/2003
3Hepatitis C
12/2014 - 01/2004
3Chronic Hepatitis B
01/2005 - 05/2002
3Cysts
12/2004 - 12/2003
3Biliary Liver Cirrhosis (Primary Biliary Cirrhosis)
05/2004 - 01/2003
3Pathologic Constriction (Stenosis)
05/2004 - 06/2002
2Microsatellite Instability
08/2022 - 06/2021
2Bullous Pemphigoid (Pemphigoid)
06/2021 - 03/2021

Drug/Important Bio-Agent (IBA)

18InterferonsIBA
01/2020 - 12/2002
12DNA (Deoxyribonucleic Acid)IBA
12/2014 - 01/2003
10CarbohydratesIBA
03/2022 - 01/2003
9Aspartate Aminotransferases (Aspartate Transaminase)IBA
01/2021 - 03/2003
9Collagen Type IV (Type IV Collagen)IBA
12/2017 - 01/2003
9Anti-Infective Agents (Microbicides)IBA
12/2014 - 04/2005
8SolventsIBA
04/2020 - 01/2014
8propylene dichlorideIBA
04/2020 - 01/2014
7AntigensIBA
03/2022 - 01/2003
7alpha-Fetoproteins (alpha-Fetoprotein)IBA
01/2020 - 07/2002
6AlbuminsIBA
01/2022 - 10/2003
6Antiviral Agents (Antivirals)IBA
11/2021 - 11/2012
6Serum AlbuminIBA
01/2021 - 07/2004
6Methylene Chloride (Dichloromethane)IBA
04/2020 - 01/2014
6Indocyanine Green (Cardio-Green)FDA LinkGeneric
09/2018 - 04/2003
6BilirubinIBA
11/2017 - 01/2003
6gamma-Glutamyltransferase (gamma-Glutamyl Transpeptidase)IBA
07/2016 - 01/2014
6Alanine Transaminase (SGPT)IBA
01/2014 - 07/2004
6Hepatitis B Surface Antigens (HBsAg)FDA Link
09/2012 - 04/2003
5MicroRNAs (MicroRNA)IBA
01/2022 - 03/2013
5Biomarkers (Surrogate Marker)IBA
01/2022 - 05/2004
5Keratin-19 (Keratin 19)IBA
02/2008 - 10/2003
4GemcitabineFDA Link
12/2021 - 10/2014
4Bile Pigments (Bilin)IBA
12/2020 - 01/2014
4Carcinoembryonic AntigenIBA
01/2020 - 03/2002
4Anti-Bacterial Agents (Antibiotics)IBA
10/2019 - 12/2003
4Aspartic Acid (Aspartate)FDA Link
03/2018 - 10/2004
3pembrolizumabIBA
08/2022 - 03/2021
3Cysteine (L-Cysteine)FDA Link
05/2022 - 04/2015
3phytobacteriomycin (PBM)IBA
03/2021 - 03/2019
3CA-19-9 Antigen (CA 19-9 Antigen)IBA
01/2020 - 02/2008
3Tumor Biomarkers (Tumor Markers)IBA
10/2019 - 12/2003
3Alanine (L-Alanine)FDA Link
03/2018 - 01/2003
3S-allylcysteine (allyl cysteine)IBA
05/2015 - 12/2009
3Vitamin K 2 (Vitamin K2)IBA
09/2007 - 04/2002
3Proteins (Proteins, Gene)FDA Link
01/2006 - 06/2002
3ParaffinIBA
05/2005 - 07/2002
3Keratins (Keratin)IBA
05/2004 - 04/2002
2Glutathione (Reduced Glutathione)IBA
05/2022 - 01/2018
2CytoglobinIBA
05/2022 - 04/2015
2AntioxidantsIBA
05/2022 - 09/2013
2Type 2 Fibroblast Growth Factor Receptor (Fibroblast Growth Factor Receptor 2)IBA
11/2021 - 05/2021
2Immune Checkpoint InhibitorsIBA
06/2021 - 11/2020
2Pharmaceutical PreparationsIBA
05/2021 - 01/2021
2Fetal Proteins (Fetoprotein)IBA
01/2021 - 10/2020

Therapy/Procedure

54Therapeutics
01/2022 - 01/2001
30Hepatectomy
01/2022 - 09/2003
12Drug Therapy (Chemotherapy)
03/2022 - 09/2002
12Liver Transplantation
10/2020 - 09/2003
10Laparotomy
01/2020 - 03/2002
8Radiofrequency Ablation
01/2022 - 01/2003
7Lymph Node Excision (Lymph Node Dissection)
01/2022 - 05/2004
7Pancreaticoduodenectomy
01/2022 - 07/2002
7Cholecystectomy
12/2020 - 01/2002
6Aftercare (After-Treatment)
01/2016 - 07/2002
5Segmental Mastectomy (Lumpectomy)
07/2022 - 11/2005
5Blood Transfusion (Blood Transfusions)
01/2018 - 07/2004
4Neoadjuvant Therapy
01/2022 - 07/2015
4Transplantation
12/2014 - 09/2003
3Operative Surgical Procedures
05/2022 - 10/2015
3Adjuvant Chemotherapy
01/2022 - 04/2014
3Length of Stay
02/2017 - 06/2003
2Sutures (Suture)
09/2021 - 03/2003